‘Clinical evaluation’ means a systematic and planned process to continuously generate, collect, analyse and assess the clinical data pertaining to a device in order to verify the safety and performance, including clinical benefits, of the device when used as intended by the manufacturer (EU MDR 2017/745). Continue

The characteristically folded surface morphology is a classical hallmark of the mammalian brain. During development, the initially smooth surface evolves into an elaborately convoluted pattern, which closely correlates with brain function and serves as a clinical indicator for physiological and pathological conditions. Continue

Pancreatic cancer is, worldwide, the 6th most frequent cause of cancer death. Of all cancers it has the most abysmal five-year survival rate. This is due to a lack of sufficiently early detection methods and the fact that, if detected, the cancer has already spread. Continue

In 2013, the American Psychiatric Association included internet gaming disorder (IGD) in the appendix of the fifth version of the Diagnostic and Statistical Manual for Mental Disorders (DSM-5) as a condition warranting further research. Continue

Understanding the plasticity of cancer cells
Despite the progresses made in the last years with the development of novel targeted agents, cancer is still a very deadly disease. This could be attributable in part to the fact that only a minority of selected patients benefit from the novel compounds,... Continue

The technology field Medical Technology from the Institute for Factory Automation and Production Systems (FAPS) merges competences of the different research groups of the chair concerning all activities in the area of medical technology. Continue

In the Chair of Digital Health, we focus on four research areas: knowledge extraction, health markers, ubiquitous systems, biosystems modeling. Our goal is to create devices, algorithms, and health markers that acquire, interpret and manage health information. Continue

In nanosized and nanostructured materials a complex interplay between electrostatics on nm length scales, dimensionality, surface properties, non-classical energy dependences and fundamental symmetry breaking is present. Continue

The electrospinning technique is widely used for the fabrication of micro- and nanofibrous structures for numerous applications in the biomedical field, e.g. tissue engineering scaffolds and drug delivery systems. Continue

Humans learn on a life-long basis -- they can perpetually address challenges and adjust to new circumstances. This ability owes itself to the flexibility of the brain, its so-called plasticity. At the same time, we can rely on memories and experiences from our entire lives, which in turn requires a ... Continue

“Virtual Cells” is a user-friendly web platform for the visualization and network analysis of high throughput data (HTD). In this platform anyone can analyze their own pre-loaded HTD sets. The tool is free to use and requires only basic notions of network biology.

At the moment, you can access:
... Continue

MELC (multi-epitope-ligand-cartography) technology enables the simultaneous staining of different tissue sections with up to 100 antibodies (Schubert et al.2006; Ostalecki et al.2016). This allows a topographic mapping of the protein expression profiles in tissue. The expression of specific markers ... Continue